ch3 I 3
CH3 — C—O—CH2 — CH2—N+ — CH3 + CoA—SH
Synaptic vesicles take up and concentrate acetylcholine from the cytosol against a steep concentration gradient, using an H+/acetylcholine antiporter in the vesicle membrane. Curiously, the gene encoding this antiporter is contained entirely within the first intron of the gene encoding choline acetyl-transferase, a mechanism conserved throughout evolution for ensuring coordinate expression of these two proteins. Different H+/neurotransmitter antiport proteins are used for import of other neurotransmitters into synaptic vesicles.
Was this article helpful?
Discover secrets, myths, truths, lies and strategies for dealing effectively with cholesterol, now and forever! Uncover techniques, remedies and alternative for lowering your cholesterol quickly and significantly in just ONE MONTH! Find insights into the screenings, meanings and numbers involved in lowering cholesterol and the implications, consideration it has for your lifestyle and future!