Effect of microinjected antibodies directed against COPI proteins on the transport of wild type Shiga toxin B-subunit or Shiga toxin B-KDEL from Golgi complex to the ER.

What evidence do these results provide for or against transport of wild-type Shiga toxin B subunit from the Golgi complex to the ER in COPI-coated vesicles? What is the importance of the results with B-KDEL in interpreting the overall results of these experiments?

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