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Cell body movement ■

▲ FIGURE 19-26 Steps in keratinocyte movement. In a fast-moving cell such as a fish epidermal cell, movement begins with the extension of one or more lamellipodia from the leading edge of the cell (1); some lamellipodia adhere to the substratum by focal adhesions (2|). Then the bulk of the cytoplasm in the cell body flows forward ( 3). The trailing edge of the cell remains attached to the substratum until the tail eventually detaches and retracts into the cell body ( 4|). See text for more discussion.

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