Philadelphia chromosome

Philadelphia chromosome der (22)

▲ EXPERIMENTAL FIGURE 10-29 Chromosomal translocations can be analyzed using banding patterns and multicolor FISH. Characteristic chromosomal translocations are associated with certain genetic disorders and specific types of cancers. For example, in nearly all patients with chronic myelogenous leukemia, the leukemic cells contain the Philadelphia chromosome, a shortened chromosome 22 [der

(22)], and an abnormally long chromosome 9 [der (9)]. These result from a translocation between normal chromosomes 9 and 22. This translocation can be detected by classical banding analysis (a) and by multicolor FISH (b). [Part (a) from J. Kuby, 1997, Immunology, 3d ed., W. H. Freeman and Company, p. 578; part (b) courtesy of J. Rowley and R. Espinosa.]

10 Ways To Fight Off Cancer

10 Ways To Fight Off Cancer

Learning About 10 Ways Fight Off Cancer Can Have Amazing Benefits For Your Life The Best Tips On How To Keep This Killer At Bay Discovering that you or a loved one has cancer can be utterly terrifying. All the same, once you comprehend the causes of cancer and learn how to reverse those causes, you or your loved one may have more than a fighting chance of beating out cancer.

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