H

OH OH Incoming rNTP

▲ FIGURE 4-9 Polymerization of ribonucleotides by RNA polymerase during transcription. The ribonucleotide to be added at the 3' end of a growing RNA strand is specified by base pairing between the next base in the template DNA strand and the complementary incoming ribonucleoside triphosphate (rNTP). A phosphodiester bond is formed when RNA polymerase catalyzes a reaction between the 3' O of the growing strand and the a phosphate of a correctly base-paired rNTP RNA strands always are synthesized in the 5'n3' direction and are opposite in polarity to their template DNA strands.

Stages in Transcription To carry out transcription, RNA polymerase performs several distinct functions, as depicted in Figure 4-10. During transcription initiation, RNA poly-merase recognizes and binds to a specific site, called a promoter, in double-stranded DNA (step 1 ). Nuclear RNA

10 Ways To Fight Off Cancer

10 Ways To Fight Off Cancer

Learning About 10 Ways Fight Off Cancer Can Have Amazing Benefits For Your Life The Best Tips On How To Keep This Killer At Bay Discovering that you or a loved one has cancer can be utterly terrifying. All the same, once you comprehend the causes of cancer and learn how to reverse those causes, you or your loved one may have more than a fighting chance of beating out cancer.

Get My Free Ebook


Post a comment