Pisatin (6.23) is an isoflavonoid phytoalexin that is synthesized by pea (Pisum sativum L.) as a response to infection (Preisig et al., 1989). Subsequently, it was shown that pathogens capable of demethylating pisatin were tolerant of this phytoalexin. The enzyme responsible for demethylation is a specific cytochrome P450 mono-oxygenase released by the fungus Nectria haematococca (Delserone et al., 1999).


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