The ability of certain drugs to increase both fluid and electrolyte loss has led to their use in the clinical management of fluid and electrolyte disorders, for example, edema. Regardless of the cause of the syndrome associated with edema, the common factor is almost invariably an increased retention of Na+. The aim of diuretic therapy is to enhance Na+ excretion, thereby promoting negative Na+ balance. This net Na+ (and fluid) loss leads to contraction of the overexpanded extracellular fluid compartment.
Was this article helpful?
If you suffer with asthma, you will no doubt be familiar with the uncomfortable sensations as your bronchial tubes begin to narrow and your muscles around them start to tighten. A sticky mucus known as phlegm begins to produce and increase within your bronchial tubes and you begin to wheeze, cough and struggle to breathe.