Uses Of Diuretics

The ability of certain drugs to increase both fluid and electrolyte loss has led to their use in the clinical management of fluid and electrolyte disorders, for example, edema. Regardless of the cause of the syndrome associated with edema, the common factor is almost invariably an increased retention of Na+. The aim of diuretic therapy is to enhance Na+ excretion, thereby promoting negative Na+ balance. This net Na+ (and fluid) loss leads to contraction of the overexpanded extracellular fluid compartment.

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