Unstable Angina and Myocardial Infarction

In patients with unstable angina and severe ischemia requiring hospital admission, therapeutic doses of heparin along with antiplatelet therapy (discussed later) are thought to provide additive protection of the patient against myocardial reinfarction. Thrombolytic drugs are more effective than anticoagulants in treating coronary thromboembolism and in establishing reperfusion of occluded arteries after an infarction. Anticoagulants in combination with antiplatelet drugs reduce the incidence of thrombus formation and reocclusion after coronary arterial bypass surgery and percutaneous coronary angioplasty.

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