The difference between the abused and the lethal dose of LSD is very large, so little pharmacological intervention is necessary. Treatment involves limiting external stimuli and placing the individual in a safe environment.
Treatment of PCP intoxication also involves limiting external stimuli, minimizing lighting, noise, and unnecessary physical contact. The life-threatening nature of PCP overdose, however, may require symptomatic treatment of respiratory depression by artificial respiration or use of neuroleptics to control violent rage or panic anxiety.
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