Since there is no cure for parkinsonism, the aim of pharmacological therapy is to provide symptomatic relief. This is obtained through the use of drugs that either increase dopaminergic actions or diminish neuronal outflow from the striatum. These drugs include levodopa, which increases brain dopamine levels; dopamine agonists, which directly stimulate dopamine receptors; monoamine oxidase (MAO) inhibitors, which prevent dopamine metabolism; and anticholinergic agents, which reduce the excitatory activity within the striatum (Fig 31.3).
Was this article helpful?
This guide will help millions of people understand this condition so that they can take control of their lives and make informed decisions. The ebook covers information on a vast number of different types of neuropathy. In addition, it will be a useful resource for their families, caregivers, and health care providers.