The Sulfonylurea Receptor

The sulfonylurea receptor was identified as an adeno-sine triphosphate (ATP) sensitive potassium (KATP) channel that is present on the ¡-cell membrane surface. Closure of these KATP channels causes ¡-cell membrane

TABLE 67.4 Pharmacokinetic Properties of Oral Hypoglycemic Drugs


Half-Life (hr)

Duration of Action (hr)

Activity of Metabolites


Blood Pressure Health

Blood Pressure Health

Your heart pumps blood throughout your body using a network of tubing called arteries and capillaries which return the blood back to your heart via your veins. Blood pressure is the force of the blood pushing against the walls of your arteries as your heart beats.Learn more...

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