The Normal Cell Cycle

The normal cell cycle consists of a definable sequence of events that characterize the growth and division of cells and can be observed by morphological and biochemical means. The cell cycle is depicted in Fig. 55.1. Two of the four phases of the cell cycle can be studied directly: the M-phase, or mitosis, is easily visible using light microscopy because of chromosomal condensation, spindle formation, and cell division. The S-phase is the period of DNA synthesis and is observed by measuring the incorporation of tritiated thymidine into cell nuclei.

The mitotic index is the fraction or percentage of cells in mitosis within a given cell population. The thymidine labeling index is the fraction of cells incorporating radioactive thymidine. They represent cells in M-phase and S-phase and define the proliferative characteristics of normal and tumor cells.

Peripheral Neuropathy Natural Treatment Options

Peripheral Neuropathy Natural Treatment Options

This guide will help millions of people understand this condition so that they can take control of their lives and make informed decisions. The ebook covers information on a vast number of different types of neuropathy. In addition, it will be a useful resource for their families, caregivers, and health care providers.

Get My Free Ebook


Post a comment