Structure and Mechanism of Action

Bacitracin is a mixture of polypeptide antibiotics produced by Bacillus subtilis. As with penicillin, it contains a thiazolidine nucleus attached through L-leucine to a pep-tide composed of both D- and L-amino acids. However, it does not contain a (3-lactam ring. Bacitracin prevents cell wall synthesis by binding to a lipid pyrophosphate carrier that transports cell wall precursors to the growing cell wall.

Bacitracin inhibits the dephosphorylation of this lipid carrier, a step essential to the carrier molecule's ability to accept cell wall constituents for transport.

Constipation Prescription

Constipation Prescription

Did you ever think feeling angry and irritable could be a symptom of constipation? A horrible fullness and pressing sharp pains against the bladders can’t help but affect your mood. Sometimes you just want everyone to leave you alone and sleep to escape the pain. It is virtually impossible to be constipated and keep a sunny disposition. Follow the steps in this guide to alleviate constipation and lead a happier healthy life.

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