Bacitracin is a mixture of polypeptide antibiotics produced by Bacillus subtilis. As with penicillin, it contains a thiazolidine nucleus attached through L-leucine to a pep-tide composed of both D- and L-amino acids. However, it does not contain a (3-lactam ring. Bacitracin prevents cell wall synthesis by binding to a lipid pyrophosphate carrier that transports cell wall precursors to the growing cell wall.
Bacitracin inhibits the dephosphorylation of this lipid carrier, a step essential to the carrier molecule's ability to accept cell wall constituents for transport.
Was this article helpful?
This guide will help millions of people understand this condition so that they can take control of their lives and make informed decisions. The ebook covers information on a vast number of different types of neuropathy. In addition, it will be a useful resource for their families, caregivers, and health care providers.