Special Considerations

Several problems unique to pediatric drug therapy deserve special mention. For example, most medications are commercially available only in adult dose forms. Preparing pediatric doses from adult tablets or capsules can be very difficult and may require special skill on the part of the pharmacist. For some drugs it is simpler to administer the intravenous (IV) preparation orally than to develop a preparation from the oral medication.

IV drug administration is most effective in children when given via a pump infusion system close to the site of IV insertion. Because of the small size of many pedi-atric doses and the fact that some drugs adhere to IV tubing, a significant percentage of the drug can be lost if

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