Recommendations For Treatment Of Active Tuberculosis

The most commonly used regimen for drug-susceptible tuberculosis consists of isoniazid, rifampin, and pyrazinamide daily for 2 months, followed by isoniazid and rifampin daily or two to three times a week for 4 months. If isoniazid resistance is suspected, ethambutol or streptomycin should be added to the regimen until the susceptibility of the mycobacterium is determined. This regimen will provide at least two drugs to which the M. tuberculosis isolate is susceptible in more than 95% of patients in the United States.

Alternative regimens include isoniazid, rifampin, pyrazinamide, and either streptomycin or ethambutol for 2 weeks followed biweekly with the same regimen for 6 weeks, and subsequently with biweekly administration of isoniazid and rifampin for 16 weeks. In HIV-infected patients the treatment should be prolonged 9 to 12 months or sometimes even longer if the response is slow. Treatment of tuberculosis is more challenging in an HIV-infected population taking highly active anti-retroviral therapy because of drug interactions.

Was this article helpful?

0 0
10 Ways To Fight Off Cancer

10 Ways To Fight Off Cancer

Learning About 10 Ways Fight Off Cancer Can Have Amazing Benefits For Your Life The Best Tips On How To Keep This Killer At Bay Discovering that you or a loved one has cancer can be utterly terrifying. All the same, once you comprehend the causes of cancer and learn how to reverse those causes, you or your loved one may have more than a fighting chance of beating out cancer.

Get My Free Ebook


Post a comment