Quaternary Ammonium Agents

Edrophonium (Enlon, Tensilon) and ambenonium (Mytelase) are monoquaternary and bisquaternary ammonium alcohols, respectively. Their positive charge allows them to bind to the anionic site at the reactive center, competitively displacing ACh from the active site without covalent modification of the site. Edrophonium has a very short duration of action, lasting only 5 to 10 minutes, whereas inhibition by ambenonium can last 4 to 8 hours. These drugs have direct agonist activity at nicotinic receptors.

Blood Pressure Health

Blood Pressure Health

Your heart pumps blood throughout your body using a network of tubing called arteries and capillaries which return the blood back to your heart via your veins. Blood pressure is the force of the blood pushing against the walls of your arteries as your heart beats.Learn more...

Get My Free Ebook

Post a comment