Pharmacokinetics

The pharmacokinetic characteristics of acebutolol:

Oral bioavailability 70%

Onset of action 1-3 hours

Peak response Duration of action Plasma half-life Primary route of metabolism Primary route of excretion

Therapeutic serum concentration

3-8 hours 12-24 hours 3-4 hours Hepatic

fecal (50-60%) Not established

Clinical Uses

Acebutolol is effective in the management of the patient with essential hypertension, angina pectoris, and ventricular arrhythmias. Antiarrhythmic effects are observed with the patient both at rest and taking exercise.

Blood Pressure Health

Blood Pressure Health

Your heart pumps blood throughout your body using a network of tubing called arteries and capillaries which return the blood back to your heart via your veins. Blood pressure is the force of the blood pushing against the walls of your arteries as your heart beats.Learn more...

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