Organ Toxicity

The events that initiate cell death are not completely understood. The common final stages of necrotic cell death are disruption of normal metabolic processes and ensuing inability to maintain intracellular electrolyte homeostasis. If the insult is severe or prolonged enough, the cell will not regain normal function. At the same time, other cells show apoptotic cell death, characterized by cell shrinkage, cleavage of DNA between nucle-osomes, and formation of apoptotic bodies. Some chemicals are metabolized to reactive products that bind to cellular macromolecules. If such binding impairs the function of crucial macromolecules, cell viability is lost. How severely organ function will be impaired depends on the reserve capacity of that organ. The ultimate outcome will depend on the affected organ's regenerative capacity and response to damage.

Peripheral Neuropathy Natural Treatment Options

Peripheral Neuropathy Natural Treatment Options

This guide will help millions of people understand this condition so that they can take control of their lives and make informed decisions. The ebook covers information on a vast number of different types of neuropathy. In addition, it will be a useful resource for their families, caregivers, and health care providers.

Get My Free Ebook

Post a comment