Ophthalmological Infection

Because of the very high concentrations of gentamicin achieved in the conjunctival sac, it is effective against nearly all of the typical bacterial pathogens that cause conjunctivitis. Special high-dose formulations of gentam-icin are necessary for treating bacterial ophthalmic ker-atitis. Gentamicin is not active against viral conjunctivitis, although it may prevent a secondary bacterial infection. Bacterial endophthalmitis, an infection of the vitreous humor, usually requires both vitreous aspiration and in-travitreal instillation of gentamicin and cefazolin.

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