Nonlinear Pharmacokinetics

The underlying assumption in the discussion of these concepts is that the drug of interest follows linear phar-macokinetic principles; that is, the concentrations achieved are proportional to the dose given. For example, a doubling of the dose will produce a doubling of the blood concentration. For some drugs, however, this is not the case: an increase in dose may produce a concentration much greater than expected. For example, increases in dosage of the antiepileptic agent phenytoin above approximately 300 mg daily usually produce a

Peripheral Neuropathy Natural Treatment Options

Peripheral Neuropathy Natural Treatment Options

This guide will help millions of people understand this condition so that they can take control of their lives and make informed decisions. The ebook covers information on a vast number of different types of neuropathy. In addition, it will be a useful resource for their families, caregivers, and health care providers.

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