Mechanism of Action

Thrombolytic drugs are plasminogen activators. The ideal thrombolytic agent is one that can be administered intravenously to produce clot-selective fibrinolysis without activating plasminogen to plasmin in plasma. Older (first generation) thrombolytic agents are not clot selective, and appreciable systemic fibrinogenolysis accompanies successful clot lysis. Newer (second generation) thrombolytic agents bind to fibrin and activate fibrinoly-sis more than fibrinogenolysis. Third-generation agents have improved fibrin specificity and pharmacokinetic properties.

Peripheral Neuropathy Natural Treatment Options

Peripheral Neuropathy Natural Treatment Options

This guide will help millions of people understand this condition so that they can take control of their lives and make informed decisions. The ebook covers information on a vast number of different types of neuropathy. In addition, it will be a useful resource for their families, caregivers, and health care providers.

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