The macrolide antibiotics (see Chapter 47) clar-ithromycin and azithromycin have demonstrated in vitro activity against mycobacteria, although they have limited activity against M. tuberculosis. Clarithromycin is four times as active as azithromycin against M. avium-intracellulare in vitro. Azithromycin's lower potency may be compensated for by its greater intracellular penetration and its two-fold higher tissue levels than plasma levels. Clarithromycin with azithromycin, in combination with other drugs, has gained an important role in the prevention and treatment of MAC in HIV-infected patients.

10 Ways To Fight Off Cancer

10 Ways To Fight Off Cancer

Learning About 10 Ways Fight Off Cancer Can Have Amazing Benefits For Your Life The Best Tips On How To Keep This Killer At Bay Discovering that you or a loved one has cancer can be utterly terrifying. All the same, once you comprehend the causes of cancer and learn how to reverse those causes, you or your loved one may have more than a fighting chance of beating out cancer.

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