All of the penicillin antibiotics are classified by the U. S. Food and Drug Administration (FDA) in pregnancy category B, that is, as drugs having either no fetal risk in animal studies but human trials are inadequate, or animal studies show adverse fetal effects but well-controlled human trials reveal no fetal damage. Obstetricians frequently prescribe ampicillin, penicillin G, and penicillin V because they are effective against the infections most frequently encountered in caring for pregnant women (e.g., upper respiratory and lower urinary tract infections).
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