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A 35-year-old mother of two has moderate psoriasis. She tells you that her mother had a similar condition 3 years ago and was successfully treated with the agent acitretin. She has come to you because her regular physician refused to write her a prescription for acitretin, and she is very uncomfortable with her skin condition. You tell her that there is a serious risk of teratogenicity if she should become pregnant. She informs you that she is taking oral contraceptives and that the possibility of pregnancy is very low. Do you prescribe the drug she has requested anyway?

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Wolverton SE. (ed.). Comprehensive Dermatologic Drug Therapy. Philadelphia: Saunders, 2001.

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Answer: Acitretin should not be prescribed for women of childbearing potential unless no acceptable alternative is available and the patient has acknowledged in writing that she understands the need to use two effective forms of contraception during therapy and for 3 years after she discontinues the drug. She has not yet been treated with PUVA. You convince her that this is a more appropriate therapy, considering her age and her childbearing potential. She grudgingly accepts your suggestions and begins a course of PUVA treatment. She responds well to the treatment, and after 6 months the psoriasis is greatly improved and treatment is terminated.

Case Study Treatment May Be Worse Than the Condition

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Drugs for the Control of Supragingival Plaque

Angelo Mariotti and Arthur F. Hefti

Natural Treatments For Psoriasis

Natural Treatments For Psoriasis

Do You Suffer From the Itching and Scaling of Psoriasis? Or the Chronic Agony of Psoriatic Arthritis? If so you are not ALONE! A whopping three percent of the world’s populations suffer from either condition! An incredible 56 million working hours are lost every year by psoriasis sufferers according to the National Psoriasis Foundation.

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