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Cholinomimetic drugs can elicit some or all of the effects that acetylcholine (ACh) produces. This class of drugs includes agents that act directly as agonists at cholinoreceptors and agents that act indirectly by inhibiting the enzymatic destruction of endogenous ACh (i.e., cholinesterase inhibitors).The directly acting choli-nomimetics can be subdivided into agents that exert their effects primarily through stimulation of mus-carinic receptors at parasympathetic neuroeffector junctions (parasympathomimetic drugs) and agents that stimulate nicotinic receptors in autonomic ganglia and at the neuromuscular junction (see Chapter 9). This chapter focuses on the parasympathomimetic drugs and cholinesterase inhibitors. Drugs acting at nicotinic receptors are presented in Chapters 14 and 28.

Coping with Asthma

Coping with Asthma

If you suffer with asthma, you will no doubt be familiar with the uncomfortable sensations as your bronchial tubes begin to narrow and your muscles around them start to tighten. A sticky mucus known as phlegm begins to produce and increase within your bronchial tubes and you begin to wheeze, cough and struggle to breathe.

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