Info

Poisoning

Group

Examples

Antihistamines

(Hj-receptor antagonists)

Antihistamines

(Hj-receptor antagonists)

Antiparkinsonian drugs

Antipsychotics

Antispasmodics

Belladonna alkaloids and related drugs Belladonna alkaloid-containing plants

Cyclic antidepressants

Cycloplegics and mydriatics Muscle relaxants

Diphenhydramine

Chlorpheniramine

Dimenhydrinate

Benztropine

Trihexyphenidyl

Chlorpromazine

Thioridazine

Loxapine

Dicyclomine

Propantheline

Atropine

Scopolamine

Deadly nightshade

Angel's trumpet

Jimsonweed

Amitriptyline

Doxepin

Fluoxetine

Cyclopentolate

Tropicamide

Orphenadrine

Cyclobenzaprine

Source: Modified from L. Goldfrank, Goldfrank's Toxicologic Emergencies. East Norwalk, CT: Appleton & Lange, 1990.

sorbed drug, treating symptoms, and providing supportive therapy. However, any life-threatening effects (i.e., seizures, severe hypertension, hallucinations, or life-threatening arrhythmias) would justify the use of specific antidotal therapy with the cholinesterase-inhibiting compound physostigmine. Special caution should be employed if the patient has any disorder that might be aggravated by the cholinergic stimulation resulting from the use of physostigmine.

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