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aSpontaneous phase 4 depolarization. b Increase in the QTc interval.

SA, sinoatrial; D, decrease in conduction velocity; I, increase in conduction velocity; -, no significant effect with clinically relevant doses; ±, minimal effect.

aSpontaneous phase 4 depolarization. b Increase in the QTc interval.

SA, sinoatrial; D, decrease in conduction velocity; I, increase in conduction velocity; -, no significant effect with clinically relevant doses; ±, minimal effect.

that make up the class II drugs. Bear in mind the complete spectrum of cardiovascular effects of these agents when prescribing their use. For example, while patients with a normally functioning cardiovascular system may tolerate adrenergic blockade of the heart, patients with compensated heart failure, who depend on adrenergic tone to maintain an adequate cardiac output, may undergo acute congestive heart failure if prescribed any of the class II drugs. Table 16.5 summarizes the clinical use of the ß-adrenoceptor blocking drugs in the treatment of cardiac arrhythmias.

Blood Pressure Health

Blood Pressure Health

Your heart pumps blood throughout your body using a network of tubing called arteries and capillaries which return the blood back to your heart via your veins. Blood pressure is the force of the blood pushing against the walls of your arteries as your heart beats.Learn more...

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