Info

+

+++

++

+

TCA, tricyclic antidepressant;SSRI, selective serotonin reuptake inhibitor;MAOI, monoamine oxidase inhibitor.

0, no effect;+, + +, + + + indicate increasing effect.

aPriapism.

bVenlafaxine can cause a dose-dependent increase in blood pressure.

TCA, tricyclic antidepressant;SSRI, selective serotonin reuptake inhibitor;MAOI, monoamine oxidase inhibitor.

0, no effect;+, + +, + + + indicate increasing effect.

aPriapism.

bVenlafaxine can cause a dose-dependent increase in blood pressure.

at the 5-HT2A, 5HT2C, 5-HT3, and histamine receptors but has minimal affinity for muscarinic or ^-receptors. Mirtazapine does not inhibit neuronal reuptake of serotonin or norepinephrine. Weight gain and sedation are common side effects (Table 33.2); sedation necessitates dosing at bedtime. Mirtazapine does not have significant effects on cytochrome P450 isoenzymes.

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