Future Directions

Today gingivitis and periodontitis are prevented principally through mechanical plaque control; however, dentition free of supragingival and subgingival plaque is extremely difficult to accomplish and maintain. On an annual basis, Americans spend more than $750 million on oral rinsing agents, although few effective plaque-inhibiting oral rinses are available and many are associated with side effects that prohibit long-term use.

The goal of future product development is not so much an improvement in the antiplaque performance of the existing effective compounds but rather lessening of their side effects and development of better delivery systems. Products that combine various known com pounds with well-established plaque-inhibiting properties are under investigation. Among the most promising products are amine fluoride plus stannous fluoride and copper sulfate plus hexetidine. In the future, chemopre-

vention of supragingival plaque will depend on products that are effective, substantive, and safe.

^ Study Questions

1. The period during which a drug is in contact with a substrate in the oral cavity is

(A) Excretion

(B) Absorption

(C) Distribution

(D) Substantivity

(E) Drug clearance

2. Yellow or brownish extrinsic stain of teeth is a frequently observed side effect of

(A) Fluoride

(B) Triclosan

(C) Essential oils

(D) Chlorhexidine

(E) Sodium lauryl sulfate

3. The LEAST effective chemical agent for reduction of dental plaque is

(A) Triclosan

(B) Essential oils

(C) Chlorhexidine

(D) Stannous fluoride

(E) Sodium lauryl sulfate

4. Which of the following agents was combined with the PVM/MA polymer to improve substantivity?

(A) Fluoride

(B) Triclosan

(C) Essential oils

(D) Chlorhexidine

(E) Sodium lauryl sulfate

5. Which commercial product would you prescribe for a recovering alcoholic?

(D) Peridex

(E) Listerine

Aromatheray For Cynics

Aromatheray For Cynics

This eBook explains how Aromatherapy has something to do with scents and smells treating illnesses and conditions. Many people who do not like the sometimes-unpleasant side effects of prescribed medication, particularly for depression, stress, or other similar disorders, have opted to use aromatherapy to help reach the desired state of being.

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