Concentration-time profile for a hypothetical drug administered intravenously. Following intravenous dosing of a drug, blood concentrations of the drug reach a maximum almost immediately. Y-axis is logarithmic scale.

centration-time profile. Cmax is defined as the maximum concentration achieved in the blood. In Figure 5.2, Cmax can be estimated to be approximately 225 ^g/mL. The other pharmacokinetic parameter that can be easily estimated from a concentration-time profile is Tmax, or the time needed to reach maximum concentration. In Figure 5.2, the Tmax is estimated by visual inspection to be approximately 2 hours. The same drug in a formulation that permits a faster rate of absorption would have a shorter Tmax and generally a higher Cmax than the formulation with slower absorptive properties. Likewise, all other things being equal, a drug with a slower elimi

Peripheral Neuropathy Natural Treatment Options

Peripheral Neuropathy Natural Treatment Options

This guide will help millions of people understand this condition so that they can take control of their lives and make informed decisions. The ebook covers information on a vast number of different types of neuropathy. In addition, it will be a useful resource for their families, caregivers, and health care providers.

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