Figure 211

A nephron, showing the major sites and percentage (in braces) of sodium absorption along with other features of solute transport. The filtered load = GFR (180 L/day) Xplasma Na+ (140 mEq/L) or 25,200 mEq/day. About 1% of this amount is excreted in voided urine. Sites where tubular fluid is isosmotic, hypertonic, or hypotonic relative to plasma are shown. PCT, proximal convoluted tubule; LH, loop of Henle; DCT, distal convoluted tubule; CCD, cortical collecting duct; TAL, thick ascending loop.

the distal nephron. The emphasis of the following sections is on the tubular transport properties that affect or are influenced by diuretics.

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