Many drugs can enhance urine flow. For example, by increasing cardiac output in the patient with congestive heart failure, digitalis administration will mobilize edema fluid and diuresis.The term diuretic, however, is generally restricted to agents that act directly on the kidney. From a therapeutic point of view, diuretics are considered to be substances that aid in removing excess extracellular fluid and electrolytes. In the main, they accomplish this by decreasing salt and water reabsorption in the tubules.
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