Development of the Partial Pressure of a Gas in Solution

Henry's law explains the behavior of gases in solutions and can be extended to body tissues. In many ways, inhalation anesthetic agents appear to be inert gases that interact with tissues and liquids physically rather than chemically. Therefore, laws governing the physical association of gases and liquids are of paramount importance to an understanding of the pharmacokinetics of these drugs. Henry's law describes the regulation of a gas concentration in a liquid when the association of these two phases is through physical interaction alone. The law states that at equilibrium, the concentration of gas physically dissolved in a liquid is directly proportional to the partial pressure (or tension) of the agent and its affinity for the molecules of the liquids (or its solubility in the liquid).

For a clear understanding of Henry's law, it is important to consider each of its component parts.

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