Clinical Uses

Interferon-a-2a (Roferon-A) is approved for the treatment of chronic hepatitis C, hairy cell leukemia, AIDS-related Kaposi's sarcoma, and chronic phase Philadelphia chromosome-positive chronic myelogenous leukemia. Interferon-a-2b (Intron A) is indicated for hairy cell leukemia, malignant melanoma, follicular lymphoma, condylomata acuminata, AIDS-related Kaposi's sarcoma, and chronic hepatitis B and C. A combination of interferon-a-2b and ribavirin (Rebetron) is used for the treatment of chronic hepatitis C. Interferon-a-n3 (Alferon N) is a solution of purified natural human interferon-aproteins approved for the treatment of condy-lomata acuminata by intralesional injection. Interferon alfacon-1 (Infergen) is a recombinant interferon constructed from the sequences of several naturally occurring interferon-asubtypes. This recombinant protein contains the most frequently observed amino acid in each position of the sequence and exhibits in vitro specific activity at least 5 times higher than that of interferon a-2a or -2b. Interferon alfacon-1 and peg inter-feron-a-2b (PEG-Intron) are approved for the treatment of chronic hepatitis C.

Interferon (3-1a (Avonex) and interferon (3-1b (Betaseron) are used in the treatment of multiple sclerosis. Interferon ^-1b (Actimmune) is used to prevent and diminish the severity of infections associated with chronic granulomatous disease and for delaying the progression of severe, malignant osteopetrosis.

Was this article helpful?

0 0
Reducing Blood Pressure Naturally

Reducing Blood Pressure Naturally

Do You Suffer From High Blood Pressure? Do You Feel Like This Silent Killer Might Be Stalking You? Have you been diagnosed or pre-hypertension and hypertension? Then JOIN THE CROWD Nearly 1 in 3 adults in the United States suffer from High Blood Pressure and only 1 in 3 adults are actually aware that they have it.

Get My Free Ebook

Post a comment