Clinical Uses

85-90% 1-2 hours 1.5-6 hours 1-2 days 12-30 hours Hepatic

Flecainide is effective in treating most types of atrial arrhythmias. It is also used for life-threatening ventricular arrhythmias. However, flecainide should be used with extreme caution in any patient with structural heart disease. Flecainide crosses the placenta, with fetal levels reaching approximately 70% of maternal levels. In many centers, it is the second-line drug after digoxin for therapy of fetal arrhythmias. Because of the high incidence of proar-rhythmia, initiation of therapy or significant increases in dosing should be performed only on inpatients.

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