Clinical

Randomized clinical trials have been conducted to explore the safety and efficacy of digitalis in the management of CHF. The first major trial showed an improvement in quality of life but no mortality benefit. A second major clinical trial revealed that treatment with digitalis diminished the combined end points of death and hos-pitalizations but did not specifically improve overall survival. Thus, no studies have demonstrated that digitalis therapy improves survival in CHF patients. However, digitalis does decrease morbidity by diminishing the number of admissions to the hospital for symptoms such as dyspnea (shortness of breath) and fatigue. Current guidelines for the treatment of CHF indicate that physicians must at least consider including digitalis in the regimen. The consensus now is to prescribe a dose that achieves a digitalis blood level of 0.8 to 1.2 ng/dL. This lower dose reduces the incidence of side effects while optimizing the benefit.

Was this article helpful?

0 0
Constipation Prescription

Constipation Prescription

Did you ever think feeling angry and irritable could be a symptom of constipation? A horrible fullness and pressing sharp pains against the bladders can’t help but affect your mood. Sometimes you just want everyone to leave you alone and sleep to escape the pain. It is virtually impossible to be constipated and keep a sunny disposition. Follow the steps in this guide to alleviate constipation and lead a happier healthy life.

Get My Free Ebook


Post a comment