Chemistry

Insulin is a relatively simple protein consisting of 51 amino acids arranged as two polypeptide chains, an a-chain and (3-chain, connected by disulfide bonds; the latter are necessary to maintain tertiary structure and biological activity (Fig 67.1). Although the amino acid sequence and composition of animal insulins may differ slightly from those of human insulin, their biological actions are similar. Alteration of specific amino acid residues within the insulin molecule yields novel derivatives that vary in their pharmacokinetics and binding affinity for the insulin receptor. Some insulin analogues display mitogenic properties in addition to their metabolic effects.

Delicious Diabetic Recipes

Delicious Diabetic Recipes

This brilliant guide will teach you how to cook all those delicious recipes for people who have diabetes.

Get My Free Ebook


Post a comment