Cellular Uptake and Intracellular Binding of T3 to Nuclear Thyroid Hormone Receptors

Free T4 and T3 can enter cells by carrier-mediated facilitated diffusion or active transport. After gaining access to the cell interior, T4 may undergo 5'-monodeiodina-tion to yield T3. The T3 thus mixes with T3 entering the cell from the plasma and binds to nuclear TRs. The specific 5'-monodeiodinase enzyme and the level of activity vary from tissue to tissue, as does the contribution of plasma T4 to nuclear TR-bound T3.

10 Ways To Fight Off Cancer

10 Ways To Fight Off Cancer

Learning About 10 Ways Fight Off Cancer Can Have Amazing Benefits For Your Life The Best Tips On How To Keep This Killer At Bay Discovering that you or a loved one has cancer can be utterly terrifying. All the same, once you comprehend the causes of cancer and learn how to reverse those causes, you or your loved one may have more than a fighting chance of beating out cancer.

Get My Free Ebook


Post a comment