The following drugs are used primarily in the treatment of herpesviruses. Among these are herpes simplex virus-1 (HSV-1), which typically causes herpes labialis (cold sores) or herpes esophagitis; herpes simplex virus-2 (HSV-2), which is responsible for most cases of genital herpes; varicella zoster virus (VZV), which produces chickenpox and shingles; Epstein-Barr virus (EBV), which is the major cause of infectious mononucleosis; and cytomegalovirus (CMV), which can produce pneumonia, gastroenteritis, retinitis, encephalitis, and mononucleosis in immunocompromised individuals.
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