1. C. There are a large number of receptors in the body. Although many drugs are attracted to receptors, the receptors are not designed for that purpose. Antagonists also are attracted to receptors. Some receptors are on the cell surface, while others are found inside the cell.
2. B. An antagonist binds to a receptor and prevents the action of an agonist. Choice A is wrong because this combination does initiate a signal transduction process. C and D are incorrect because both neuro-transmitters and hormones work through their appropriate receptor to initiate signal transduction.
3. D. A covalent bond is a strong and stable bond that is essentially irreversibly formed at normal body temperature. The other bonds are much weaker.
4. C. Potency is a useful measure of the comparison between two or more drugs. It does not equate to therapeutic superiority but rather is a measure of the size of the dose required to produce a particular level of response.
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