Angiotensin Receptor Antagonists

Angiotensin II can bind with high affinity to two distinct receptors, termed the angiotensin type 1 (ATI) and the angiotensin type 2 (AT2) receptor. These receptors belong to a superfamily of G protein-coupled receptors that contain seven transmembrane regions. The amino acid sequence of these receptors is highly conserved across species. The AT1 and AT2 receptors share only 34% homology, have distinct signal transduction pathways, and are not necessarily found on the same cell type or tissue. As previously discussed, most of the physiological effects of angiotensin II are mediated through effects at the AT1 receptor.

10 Ways To Fight Off Cancer

10 Ways To Fight Off Cancer

Learning About 10 Ways Fight Off Cancer Can Have Amazing Benefits For Your Life The Best Tips On How To Keep This Killer At Bay Discovering that you or a loved one has cancer can be utterly terrifying. All the same, once you comprehend the causes of cancer and learn how to reverse those causes, you or your loved one may have more than a fighting chance of beating out cancer.

Get My Free Ebook


Post a comment