Alzheimers Disease

Alzheimer's disease is a slowly developing neurodegen-erative disease that produces a progress loss of memory and cognitive function, that is, dementia. These functional changes appear to result primarily from the loss of cholinergic transmission in the neocortex. The four cholinesterase inhibitors that have been approved for use in the palliative treatment of Alzheimer's disease are tacrine, donepezil, rivastigmine, and galanthamine. These agents can cross the blood-brain barrier to produce a reversible inhibition of AChE in the CNS. These compounds produce modest but significant improvement in the cognitive function of patients with mild to moderate Alzheimer's disease, but they do not delay progression of the disease. Donepezil, rivastigmine, and galanthamine are as effective as tacrine in increasing cognitive performance but do not share tacrine's hepa-totoxic effects.

Unraveling Alzheimers Disease

Unraveling Alzheimers Disease

I leave absolutely nothing out! Everything that I learned about Alzheimer’s I share with you. This is the most comprehensive report on Alzheimer’s you will ever read. No stone is left unturned in this comprehensive report.

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