Absorption Metabolism and Excretion

Because of its poor oral bioavailability, foscarnet is administered intravenously. Following intravenous infusion, 14 to 17% of foscarnet is bound to plasma proteins. The concentration of this compound in the vitreous humor is approximately the same as its plasma level. Foscarnet accumulates in bone; this property may account for its bimodal initial half-life of 4 to 8 hours and prolonged terminal elimination half-life of 45 to 130 hours. Foscarnet is eliminated primarily as unchanged drug via glomerular filtration and active tubular secretion.

Peripheral Neuropathy Natural Treatment Options

Peripheral Neuropathy Natural Treatment Options

This guide will help millions of people understand this condition so that they can take control of their lives and make informed decisions. The ebook covers information on a vast number of different types of neuropathy. In addition, it will be a useful resource for their families, caregivers, and health care providers.

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