Absorption Metabolism and Excretion

Because of its poor oral bioavailability, foscarnet is administered intravenously. Following intravenous infusion, 14 to 17% of foscarnet is bound to plasma proteins. The concentration of this compound in the vitreous humor is approximately the same as its plasma level. Foscarnet accumulates in bone; this property may account for its bimodal initial half-life of 4 to 8 hours and prolonged terminal elimination half-life of 45 to 130 hours. Foscarnet is eliminated primarily as unchanged drug via glomerular filtration and active tubular secretion.

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Bacterial Vaginosis Facts

Bacterial Vaginosis Facts

This fact sheet is designed to provide you with information on Bacterial Vaginosis. Bacterial vaginosis is an abnormal vaginal condition that is characterized by vaginal discharge and results from an overgrowth of atypical bacteria in the vagina.

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