Absorption Metabolism and Excretion

Sulfonylureas are readily absorbed from the gastrointestinal tract following oral administration but undergo varying degrees and rates of metabolism in the liver and/or kidney; some metabolites possess intrinsic hy-poglycemic activity. Thus, the biological half-lives of the sulfonylureas vary greatly, and a comparison of the drug half-life with the observed duration of action does not always show a good correlation. Sulfonylureas and their metabolites are excreted either renally or in the feces.

Peripheral Neuropathy Natural Treatment Options

Peripheral Neuropathy Natural Treatment Options

This guide will help millions of people understand this condition so that they can take control of their lives and make informed decisions. The ebook covers information on a vast number of different types of neuropathy. In addition, it will be a useful resource for their families, caregivers, and health care providers.

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