Absorption Metabolism and Excretion

Zanamivir has a bioavailability of less than 5% when absorbed through the gastrointestinal tract. It is administered using a breath-actuated inhaler device (Diskhaler)

that delivers the drug as an aerosol in a lactose carrier. The lactose particles are large, and about 78% deposit in the oropharynx. Following oral inhalation, zanamivir has a bioavailability of 12 to 17%, with peak plasma concentrations being reached within 1.5 hours. It is rapidly eliminated by the kidneys without significant metabolism and has a plasma elimination half-life of 2.5 to 5 hours.

Nicotine Support Superstar

Nicotine Support Superstar

Stop Nicotine Addiction Is Not Easy, But You Can Do It. Discover How To Have The Best Chance Of Quitting Nicotine And Dramatically Improve Your Quality Of Your Life Today. Finally You Can Fully Equip Yourself With These Must know Blue Print To Stop Nicotine Addiction And Live An Exciting Life You Deserve!

Get My Free Ebook


Post a comment