A2Adrenoceptor Agonists

^-Adrenoceptor agonists have received attention for their ability to produce sedation and analgesia. Their sedative properties may be related to action on a2-re-ceptors in the locus ceruleus, and analgesia likely occurs via a2-receptors in the spinal cord and locus ceruleus. Agents used when sedation is desirable include oral clonidine (Catapres) and IV dexmedetomidine (Prece-dex), which has recently been approved in the United States for sedation in intensive care units. A solution of clonidine (Duraclon) is also available to provide or as a supplement for epidural analgesia. Hypnosis sufficient for surgical anesthesia is not adequate when the a2-adrenoceptor agonists are used alone, and cardiovascular side effects, including bradycardia and hypotension, limit the doses that can be used. As adjunctive drugs they significantly reduce the dose requirement for opi-oids and anesthetics during surgery.

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Advanced Hypnosis For Newbies

Advanced Hypnosis For Newbies

For anyone concerned that this is a report designed to teach readers how to convince crowds of people to act like chickens or dance to an unheard song just with a carefully placed keyword - relax. While hypnosis is often paraded in that form with large crowds visiting celebrity hypnosis experts to see what wonders they can perform, the majority of hypnosis used is to aid people seeking a solution to a problem they cannot resolve easily with any other method.

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