Comorbidity of Axis I and Axis II Disorders

Those with a personality disorder are selectively at greater risk of developing an Axis I disorder, especially mood, anxiety, and somatization disorders (Zweig, 2003). As discussed earlier, we know that Axis I and II disorders commonly coexist in about 20% to 75% of patients (DeLeo, Scocco, & Meneghel, 1999; Oldham, 2001; Widiger & Seidlitz, 2002). Comorbid depression is especially prevalent, with approximately 15% to 30% of older adults diagnosed with depression also having a comorbid personality disorder (Devanand, 2002; Kunik et al., 1994). Most of the personality disorders fall into Cluster C (Abrams et al., 1987, 1994; Devanand, 2002; Kean et al., 2004).

The age of onset of the depression appears to relate to the probability of comorbidity. Patients who have early onset depression are more likely to have a comorbid personality disor der than those with late onset depression (Devanand, 2002; Kunik et al., 1994).

Those diagnosed with a personality disorder have also been shown to have a higher rate of anxiety disorders. Generalized Anxiety Disorder, the most prevalent anxiety disorder among older adults, has been shown to have a high comorbidity with personality disorders, specifically with Cluster C personality disorders (Coolidge, Segal, et al., 2000; Kean et al., 2004).

Anxiety and Depression 101

Anxiety and Depression 101

Everything you ever wanted to know about. We have been discussing depression and anxiety and how different information that is out on the market only seems to target one particular cure for these two common conditions that seem to walk hand in hand.

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