The diagnosis of IC is suspected by the clinician, because no objective test exists. In August 1987, the National Institute of Diabetes and Digestive and Kidney Diseases (NIDDKD) established criteria to diagnose IC for research purposes.32 However, the criteria were strict and patients meeting these criteria had advanced disease. Application of these criteria in routine clinical practice will miss 60% of patients with IC.33 The NIDDKD in association with the IC Association is currently developing a broader definition for IC/painful bladder syndrome.

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