Pneumocystis carinii

Pneumocystis carinii was earlier considered a protozoan parasite but recent data suggest that it is a primitive fungus (Miller and Wakefield 1996). However, since it is on the border line between fungal and parasitic diseases it is included here. Pneumocystis carinii gives severe pneumonia (PCP) in immunosuppressed patients (see Chapter 12). It became known as one of the major opportunistic diseases affecting HIV patients during the early 1980s but the number of cases in HIV-infected patients has decreased since then due to prophylactic PCP treatment and anti-virus drugs. However, pneumocystis is still detected in 50% of the samples from HIV patients investigated in Sweden; 165 cases were reported in 1998 (Olsson et al. 1999). Similar numbers were obtained in Denmark. Among these cases are also

Page 29

other immunocompromised patients, that is, malignancy patients, transplant recipients, and patients receiving immunosuppressive therapy.

0 0

Post a comment