Figure 25.5 Light microscopy of liver sections from wild-type and taut—/— mice. taut—/— mice develop variable degrees of hepatitis and fibrosis. (A and B) Chronic hepatitis with presence ofapoptotic bodies (arrow) and mixed leukocytic infiltrates (double arrow) in a19-month-old taut—/— mouse ( x100, x400). Liver tissue sections were stained with hematoxylin and eosin. (C and D) Liver fibrosis in taut—/— mouse. Liver tissue sections were stained with Sirius red. (C) Seventeen-month-old wild-type; (D) 15-month-old taut—/— mouse (magnification x100). Adapted from Warskulat et al. (2006b .

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